Of course.
I think we notice it more when we are having so much possession, but if you watch a Man City game for example, even a beast of a goal machine like Haaland misses his fair share of "easy" chances.
I remember when Roberto Baggio broke the transfer fee world record. We played Italy in a World Cup qualifier (at Ibrox) and he was put through clear on goal with enough time to pick his spot. He almost put it out for a shy.